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Tegoprazan (Standard)

Tegoprazan (Standard) is the analytical standard of Tegoprazan. This product is intended for research and analytical applications. Tegoprazan (CJ-12420), a potassium-competitive acid blocker, is a potent, oral active and highly selective inhibitor of gastric H+/K+-ATPase that could control gastric acid secretion and motility, with IC50 values ranging from 0.29-0.52 μM for porcine, canine, and human H+/K+-ATPases in vitro[1].

Product Specifications

CAS Number

942195-55-3

Product Name Alternative

CJ-12420 (Standard) ; RQ-00000004 (Standard)

UNSPSC

12352005

Target

Proton Pump; Reference Standards

Type

Reference Standards

Related Pathways

Membrane Transporter/Ion Channel; Others

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/tegoprazan-standard.html

Smiles

FC1=CC(F)=C2[C@@H](OC3=CC(C(N(C)C)=O)=CC4=C3N=C(C)N4)CCOC2=C1

Molecular Formula

C20H19F2N3O3

Molecular Weight

387.38

References & Citations

[1]Takahashi N, et al. Tegoprazan, a Novel Potassium-Competitive Acid Blocker to Control Gastric Acid Secretion and Motility. J Pharmacol Exp Ther. 2018 Feb;364 (2) :275-286.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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