Human Recombinant B7-H3/CD276 Extracellular Domain

<strong>Human Recombinant B7-H3/CD276 Extracellular Domain</strong>_x000D_ <strong>Catalog number:</strong> B2016942_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 73.4 kDa_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80°C_x000D_ <strong>Keywords:</strong> 4Ig-B7-H3, B7 Homolog 3, B7RP-2_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Shi J, Zhang DL, Cui ZC, Wang HM. Preparation and application of a novel monoclonal antibody specific for human B7-H3 Mol Med Rep. 2016 Jul;14(1):943-8._x000D_ 2: Janakiram M, Shah UA, Liu W, Zhao A, Schoenberg MP, Zang X. The third group of the B7-CD28 immune checkpoint family: HHLA2, TMIGD2, B7x, and B7-H3 Immunol Rev. 2017 Mar;276(1):26-39._x000D_ 3: Luan Y, Ju J, Luo L, Zhang Z, Wang J, Zhu DM, Cheng L, Zhang SY, Chen L, Wang FS, Wang S. Potential role of soluble B7-H3 in liver immunopathogenesis during chronic HBV infection J Viral Hepat. 2012 Jan;19(1):23-31._x000D_ 4: Feng R, Wang R, Hong J, Dower CM, Croix BS, Ho M. Isolation of rabbit single domain antibodies to B7-H3 via protein immunization and phage display Antib Ther. 2020 Jan;3(1):10-17._x000D_ 5: Sugita S, Futatsugi Y, Ishida M, Edo A, Takahashi M. Retinal Pigment Epithelial Cells Derived from Induced Pluripotent Stem (iPS) Cells Suppress or Activate T Cells via Costimulatory Signals Int J Mol Sci. 2020 Sep 5;21(18):6507._x000D_ 6: Wang R, Ma Y, Zhan S, Zhang G, Cao L, Zhang X, Shi T, Chen W. B7-H3 promotes colorectal cancer angiogenesis through activating the NF-κB pathway to induce VEGFA expression Cell Death Dis. 2020 Jan 23;11(1):55._x000D_ 7: Li L, Nian S, Liu Q, Zhang B, Jimu W, Li C, Huang Z, Hu Q, Huang Y, Yuan Q. Fully human anti-B7-H3 recombinant antibodies inhibited tumor growth by increasing T cell infiltration Int Immunopharmacol. 2024 May 10;132:111926._x000D_ 8: Feng P, Zhang H, Zhang Z, Dai X, Mao T, Fan Y, Xie X, Wen H, Yu P, Hu Y, Yan R. The interaction of MMP-2/B7-H3 in human osteoporosis Clin Immunol. 2016 Jan;162:118-24._x000D_ 9: Zhang C, Chen Y, Li F, Yang M, Meng F, Zhang Y, Chen W, Wang W. B7-H3 is spliced by SRSF3 in colorectal cancer Cancer Immunol Immunother. 2021 Feb;70(2):311-321._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/15188059">10: Zhang GB, Chen YJ, Shi Q, Ma HB, Ge Y, Wang Q, Jiang Z, Xu Y, Zhang XG. Human recombinant B7-H3 expressed in E. coli enhances T lymphocyte proliferation and IL-10 secretion in vitro Acta Biochim Biophys Sin (Shanghai). 2004 Jun;36(6):430-6. </a>_x000D_ _x000D_ <strong>Products Related to Human Recombinant B7-H3/CD276 Extracellular Domain can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>