UCHL3, Rat (His)

The UCHL3 protein is a deubiquitinating enzyme (DUB) that complexly controls cellular ubiquitin levels by processing ubiquitin precursors and ubiquitinated proteins. As a thiol protease, UCHL3 selectively recognizes and hydrolyzes the peptide bond of ubiquitin or the C-terminal glycine of NEDD8, showing a 10-fold preference for Arg and Lys at the P3 position, and has a special preference for "Lys-48" linked ubiquitin chains. affinity. UCHL3 Protein, Rat (His) is the recombinant rat-derived UCHL3 protein, expressed by E. coli , with N-His labeled tag. The total length of UCHL3 Protein, Rat (His) is 229 a.a., with molecular weight of ~28 kDa.

EGQRWLPLEA NPEVTNQFLK QLGLHPNWQF VDVYGMEPEL LSMVPRPVCA VLLLFPITEK YEVFRTEEEE KIKSQGQDVT SSVYFMKQTI SNACGTIGLI HAIANNKDKM HFESGSALKK FLEESVAMSP EERARHLENY DAIRVTHETS AHEGQTEAPS IDEKVDLHFI ALVHVDGHLY ELDGRKPFPI NHGKTSDETL LEDAIEVCKK FMERDPDELR FNAIALSAA