Erucin

Erucin (ERU) is an isothiocyanate particularly abundant in arugula. Erucin shows anticancer, neuroprotective, and anti-inflammatory activities[1][2][3][4].

Product Specifications

CAS Number

[4430-36-8]

UNSPSC

12352211

Hazard Statement

H314

Target

Apoptosis

Type

Reference compound

Related Pathways

Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/erucin.html

Purity

98.15

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CSCCCCN=C=S

Molecular Formula

C6H11NS2

Molecular Weight

161.29

Precautions

H314

References & Citations

[1]Valentina Citi, et al. Anticancer properties of erucin, an H2 S-releasing isothiocyanate, on human pancreatic adenocarcinoma cells (AsPC-1) . Phytother Res. 2019 Mar;33 (3) :845-855. |[2]A. Melchini, et al. Erucin, a new promising cancer chemopreventive agent from rocket salads, shows anti-proliferative activity on human lung carcinoma A549 cells. Food Chem Toxicol. 2009 Jul;47 (7) :1430-6.|[3]Han Jin Cho, et al. Erucin exerts anti-inflammatory properties in murine macrophages and mouse skin: possible mediation through the inhibition of NFκB signaling. Int J Mol Sci. 2013 Oct 15;14 (10) :20564-77. |[4]Fabiana Morroni, et al. Comparison of Adaptive Neuroprotective Mechanisms of Sulforaphane and its Interconversion Product Erucin in in Vitro and in Vivo Models of Parkinson's Disease. J Agric Food Chem. 2018 Jan 31;66 (4) :856-865.