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3-​O-​Acetyloleanolic acid

3-O-Acetyloleanolic acid (3AOA), an oleanolic acid derivative isolated from the seeds of Vigna sinensis K., induces in cancer and also exhibits anti-angiogenesis activity[1].

Product Specifications

CAS Number

[4339-72-4]

UNSPSC

12352211

Hazard Statement

H315, H319, H335

Target

Apoptosis

Type

Natural Products

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/3-o-acetyloleanolic-acid.html

Purity

99.84

Solubility

DMSO : 2 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

C[C@]12[C@]3(C([C@@]4([H])[C@](C(O)=O)(CCC(C)(C)C4)CC3)=CC[C@]1([H])[C@@]5([C@@](C(C)([C@@H](OC(C)=O)CC5)C)([H])CC2)C)C

Molecular Formula

C32H50O4

Molecular Weight

498.74

Precautions

H315, H319, H335

References & Citations

[1]Yoo KH, et al. 3-O-acetyloleanolic acid induces apoptosis in human colon carcinoma HCT-116 cells. Phytother Res. 2012 Oct;26 (10) :1541-6.|[2]Hwang-Bo J, et al. 3-O-Acetyloleanolic acid inhibits VEGF-A-induced lymphangiogenesis and lymph node metastasis in an oral cancer sentinel lymph node animal model. BMC Cancer. 2018 Jul 5;18 (1) :714.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

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