Quinacrine (acetate)
Quinacrine (Acriquine) acetate is a small molecule modulator of the cGAS-STING-TBK1 signaling pathway, possessing immune stimulatory activity. Quinacrine acetate has been explored for its potential therapeutic applications in enhancing anti-tumor immunity. Quinacrine acetate can improve the effectiveness of cancer immunotherapies by addressing the poor immunogenicity of various tumors. Quinacrine acetate also presents a promising strategy for overcoming the limitations associated with immune checkpoint inhibitors in cancer treatment.
Product Specifications
CAS Number
78901-94-7
Product Name Alternative
Acriquine (acetate)
UNSPSC
12352005
Target
Apoptosis; DNA Stain; Parasite; Sodium Channel
Type
Reference compound
Related Pathways
Anti-infection; Apoptosis; Cell Cycle/DNA Damage; Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/quinacrine-acetate.html
Smiles
O=C(C)O.ClC(C=CC1=C2NC(CCCN(CC)CC)C)=CC1=NC3=C2C=C(OC)C=C3
Molecular Formula
C25H34ClN3O3
Molecular Weight
460.01
References & Citations
[1]Small molecules targeting the innate immune cGAS‒STING‒TBK1 signaling pathway
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Frequently Asked Questions
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