What is the catalog number for GW6471?

The catalog number for GW6471 is HY-15372.

What sizes are available for GW6471?

GW6471 is available in the following size(s): 5 mg, 10 mg, 10 mM - 1 mL, 50 mg, 100 mg, 500 mg, 1 g.

How many pack sizes does GW6471 come in?

GW6471 is available in 7 different pack sizes.

GW6471 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures GW6471?

GW6471 is manufactured by QuantiMol.

What is the estimated delivery time for GW6471?

Estimated delivery time for GW6471 is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for GW6471?

The safety data sheet for GW6471 is available here: http://file.medchemexpress.com/batch_PDF/HY-15372/GW6471-SDS-MedChemExpress.pdf.

GW6471

GW6471 is a potent PPARα antagonist.

Product Specifications

CAS Number

880635-03-0

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

PPAR

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/GW_6471.html

Purity

99.64

Solubility

DMSO : 83.33 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CCC(NC[C@@H](N/C(C)=C\C(C1=CC=C(C(F)(F)F)C=C1)=O)CC2=CC=C(OCCC3=C(C)OC(C4=CC=CC=C4)=N3)C=C2)=O

Molecular Formula

C35H36F3N3O4

Molecular Weight

619.67

Precautions

H302, H315, H319, H335

References & Citations

[1]Xu HE, et al. Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARalpha. Nature. 2002 Feb 14;415 (6873) :813-7.|[2]Abu Aboud O, et al. Inhibition of PPARα induces cell cycle arrest and apoptosis, and synergizes with glycolysisinhibition in kidney cancer cells. PLoS One. 2013 Aug 7;8 (8) :e71115.|[3]Abu Aboud O, et al. PPARα inhibition modulates multiple reprogrammed metabolic pathways in kidney cancer and attenuates tumor growth. Am J Physiol Cell Physiol. 2015 Jun 1;308 (11) :C890-8.