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1-Bromo-2-methyl-3-nitrobenzene

1-Bromo-2-methyl-3-nitrobenzene is an organic synthesis intermediate. 1-Bromo-2-methyl-3-nitrobenzene participates in chemical reactions such as electrophilic substitution and coupling through the bromine atom and nitro group in the molecule, and acts as a synthetic precursor. 1-Bromo-2-methyl-3-nitrobenzene can construct complex molecular structures by relying on the leaving property of bromine and the electron-withdrawing property of nitro group, and can be used in the synthesis of benzimidazole VISTA inhibitors in medicinal chemistry[1].

Product Specifications

CAS Number

[55289-35-5]

UNSPSC

12352200

Hazard Statement

H315, H319, H335

Target

Biochemical Assay Reagents

Type

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/1-bromo-2-methyl-3-nitrobenzene.html

Purity

99.92

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=[N+](C1=C(C)C(Br)=CC=C1)[O-]

Molecular Formula

C7H6BrNO2

Molecular Weight

216.03

Precautions

H315, H319, H335

References & Citations

[1]Wang T, et al. Novel Benzimidazoles as Potent Small-Molecule Inhibitors and Degraders of V-Domain Ig Suppressor of T-Cell Activation (VISTA) . J Med Chem. 2023 Sep 14;66 (17) :11881-11892.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Biochemical Assay Reagents

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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