ABD-295
ABD-295, a biphenylsulfide derivative, is an antiresorptive agent, osteoclast inhibitor. ABD-295 has potent inhibitory effects on osteoclastic bone resorption in vitro. ABD-295 prevents ovariectomy-induced bone loss in vivo[1].
Product Specifications
CAS Number
871113-99-4
UNSPSC
12352005
Target
C-Fms; Nuclear Factor of activated T Cells (NFAT)
Type
Reference compound
Related Pathways
Immunology/Inflammation; Protein Tyrosine Kinase/RTK
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/abd-295.html
Smiles
O=S(C1=CC=C(C2=CC=C(F)C=C2F)C(C)=C1)(NCCCCO)=O
Molecular Formula
C17H19F2NO3S
Molecular Weight
355.40
References & Citations
[1]Iain R Greig, et al. Development and characterization of biphenylsulfonamides as novel inhibitors of bone resorption. J Med Chem. 2006 Dec 14;49 (25) :7487-92.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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