5-FAM-LL-37 (TFA)
5-FAM-LL-37 TFA is the TFA salt form of 5-FAM-LL-37. 5-FAM-LL-37 TFA is a LL-37 peptide labeled with fluorescein, which retains the antibacterial and immunomodulatory activities of LL-37. 5-FAM-LL-37 TFA binds to the bacterial cell membrane, destroys the integrity of the membrane, and exhibits board-spectrum antibacterial efficacy[1].
Product Specifications
UNSPSC
12352209
Target
Bacterial; Fluorescent Dye
Type
Peptides
Related Pathways
Anti-infection; Others
Applications
COVID-19-immunoregulation
Field of Research
Infection
Purity
95.76
Solubility
H2O : 20 mg/mL (ultrasonic)
Smiles
OC[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H]1N(CCC1)C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC(C2=CC3=C(C=C2)C4(OC3=O)C5=C(C=C(C=C5)O)OC6=C4C=CC(O)=C6)=O)CC(C)C)=O)CC(C)C)=O)=O)CC(O)=O)=O)CC7=CC=CC=C7)=O)CC8=CC=CC=C8)=O)CCCNC(N)=N)=O)CCCCN)=O)CO)=O)CCCCN)=O)CCC(O)=O)=O)CCCCN)=O)[C@H](CC)C)=O)=O)CCCCN)=O)CCC(O)=O)=O)CC9=CC=CC=C9)=O)CCCCN)=O)CCCNC(N)=N)=O)[C@H](CC)C)=O)C(C)C)=O)CCC(N)=O)=O)CCCNC(N)=N)=O)[C@H](CC)C)=O)CCCCN)=O)CC(O)=O)=O)CC%10=CC=CC=C%10)=O)CC(C)C)=O)CCCNC(N)=N)=O)CC(N)=O)=O)CC(C)C)=O)C(C)C)=O)=O)CCCNC(N)=N)=O)[C@@H](C)O)=O)CCC(O)=O)=O)C(O)=O.OC(C(F)(F)F)=O.[x]
Molecular Formula
C226H350N60O59.xC2HF3O2
Molecular Weight
4851.56 (free acid)
References & Citations
[1]Pastuszak K, et al., Insight into the Mechanism of Interactions between the LL-37 Peptide and Model Membranes of Legionella gormanii Bacteria. Int J Mol Sci. 2023 Jul 27;24 (15) :12039.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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