Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

CDDO-EA

CDDO-EA is an NF-E2 related factor 2/antioxidant response element (Nrf2/ARE) activator.

Product Specifications

CAS Number

[932730-51-3]

Product Name Alternative

CDDO ethyl amide; TP319; RTA 405

UNSPSC

12352211

Target

Keap1-Nrf2

Type

Reference compound

Related Pathways

NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/CDDO-EA.html

Concentration

10mM

Purity

99.78

Solubility

DMSO : 16.67 mg/mL (ultrasonic; warming; heat to 80°C)

Smiles

O=C1C(C#N)=C[C@@]2(C)[C@](CC[C@]([C@@]3(C)[C@@]4([H])[C@@]5([H])[C@@](CCC(C)(C)C5)(C(NCC)=O)CC3)(C)C2=CC4=O)([H])C1(C)C

Molecular Formula

C33H46N2O3

Molecular Weight

518.73

References & Citations

[1]Neymotin A, et al. Neuroprotective effect of Nrf2/ARE activators, CDDO ethylamide and CDDO trifluoroethylamide, in a mouse model of amyotrophic lateral sclerosis. Free Radic Biol Med. 2011 Jul 1;51 (1) :88-96.|[2]Liby K, et al. The synthetic triterpenoids CDDO-methyl ester and CDDO-ethyl amide prevent lung cancer induced by vinyl carbamate in A/J mice. Cancer Res. 2007 Mar 15;67 (6) :2414-9.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-12213/CDDO-EA-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-12213/CDDO-EA-SDS-MedChemExpress.pdf

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Rat Monoclonal hapten 4-hydroxy-3-nitrophenyl acetyl (NP) Antibody (B1-8) [Janelia Fluor 549]
NBP2-81028JF549 0.1 mL

Rat Monoclonal hapten 4-hydroxy-3-nitrophenyl acetyl (NP) Antibody (B1-8) [Janelia Fluor 549]

Ask
View Details
Phospho-NF-kB p65/RelA-S529 Rabbit pAb
E45R00871N-50 50 µL

Phospho-NF-kB p65/RelA-S529 Rabbit pAb

Ask
View Details
CHD3-set siRNA/shRNA/RNAi Lentivector (Human)
16041091 4 x 500 ng

CHD3-set siRNA/shRNA/RNAi Lentivector (Human)

Ask
View Details
Anti-Caspase 9 (Tyr153) CASP9 Antibody
A00080Y153 100 µL

Anti-Caspase 9 (Tyr153) CASP9 Antibody

Ask
View Details
GLI2 Antibody
E043461 100 µg -100 µL

GLI2 Antibody

Ask
View Details
Recombinant Archaeoglobus fulgidus Putative (R)-citramalate synthase CimA
MBS1145180-01 0.02 mg (E-Coli)

Recombinant Archaeoglobus fulgidus Putative (R)-citramalate synthase CimA

Ask
View Details