RFA1 rabbit pAb
Function: It participates in a very early step in initiation. RP-A is a single-stranded DNA-binding protein. Absolutely required for simian virus 40 DNA replication in vitro. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Belongs to the replication factor A protein 1 family. subunit: Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Interacts with RIP and XPA. Interacts with RPA4.
Product Specifications
Background
UniProt
P27694
Swiss Prot
P27694
Reactivity
Human; Monkey; Mouse; Rat
Immunogen
Synthesized peptide derived from human RFA1
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Nucleus . Nucleus, PML body . Enriched in PML bodies in cells displaying alternative lengthening of their telomeres. .
Other Product Names
Replication protein A 70 kDa DNA-binding subunit (RP-A p70; Replication factor A protein 1; RF-A protein 1; Single-stranded DNA-binding protein)
Gene ID (Human)
6117
Available Sizes
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