Anti-ATM Antibody

Goat Polyclonal Antibody specific to ATM

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

EC 2.7.11.1, Ataxia telangiectasia mutated, A-T mutated

Gene Name

ATM

NCBI Gene ID

UniProt

Q13315

Accession Number

NP_000042

Cellular Locus

Nucleus, Cytoplasmic vesicle, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome

Host

Goat

Reactivity

Human, Mouse

Immunogen

Synthetic peptide representing a portion of the protein encoded in part by exons 37 and 38 (LocusLink ID 472).

Target Antigen

Serine-protein kinase ATM

Target

ATM

Clonality

Polyclonal

Isotype

Whole IgG

Type

Antibody

Applications

WB, IP

Field of Research

Enzymes

Purification Method

Purified by immunoaffinity chromatography

Concentration

Lot Specific

Dilution

Dilute in PBS or medium which is identical to that used in the assay system.

Format

Purified

Form

Liquid

Buffer

Tris

Function

Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. RPubMed:10550055, PubMed:10766245, PubMed:10802669, PubMed:10839545, PubMed:10910365, PubMed:10973490, PubMed:11375976, PubMed:12086603, PubMed:12556884, PubMed:14871926, PubMed:15448695, PubMed:15456891, PubMed:15916964, PubMed:16086026, PubMed:16858402, PubMed:17923702, PubMed:19431188, PubMed:19965871, PubMed:26774286, PubMed:29203878, PubMed:30612738, PubMed:30886146, PubMed:9733514, PubMed:9733515, PubMed:9843217}.