STING agonist-38

STING agonist-38 (compound 58) is a potent agonist of STING, with the EC50 of 0.05 μM in THP1 cells. STING agonist-38 has certain oral bioactivity[1].

Product Specifications

CAS Number

[2850251-27-1]

UNSPSC

12352005

Target

STING

Type

Reference compound

Related Pathways

Immunology/Inflammation

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/sting-agonist-38.html

Smiles

O=C(C1=CC2=C(C(OC)=C1)N(CCCNC3=NC=C(C4=C(C(F)(F)F)C=CC=C4)O3)C(NC(C5=CC(C)=NN5CC)=O)=N2)N

Molecular Formula

C29H29F3N8O4

Molecular Weight

610.59

References & Citations

[1]China Pharmaceutical University. Preparation of benzimidazole compounds for treatment of STING protein function related diseases. China, CN115141182 A 2022-10-04