STING agonist-38
STING agonist-38 (compound 58) is a potent agonist of STING, with the EC50 of 0.05 μM in THP1 cells. STING agonist-38 has certain oral bioactivity[1].
Product Specifications
CAS Number
[2850251-27-1]
UNSPSC
12352005
Target
STING
Type
Reference compound
Related Pathways
Immunology/Inflammation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sting-agonist-38.html
Smiles
O=C(C1=CC2=C(C(OC)=C1)N(CCCNC3=NC=C(C4=C(C(F)(F)F)C=CC=C4)O3)C(NC(C5=CC(C)=NN5CC)=O)=N2)N
Molecular Formula
C29H29F3N8O4
Molecular Weight
610.59
References & Citations
[1]China Pharmaceutical University. Preparation of benzimidazole compounds for treatment of STING protein function related diseases. China, CN115141182 A 2022-10-04
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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