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H- (Gly) 3-Lys (N3) -OH (hydrochloride)

H- (Gly) 3-Lys (N3) -OH (hydrochloride) is a click chemistry reagent. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

Product Specifications

CAS Number

2737202-70-7

UNSPSC

12352211

Target

ADC Linker

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/h-gly-3-lys-n3-oh-hydrochloride.html

Purity

99.79

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

NCC(NCC(NCC(N[C@H](C(O)=O)CCCCN=[N+]=[N-])=O)=O)=O.Cl

Molecular Formula

C12H22ClN7O5

Molecular Weight

379.80

References & Citations

[1]Jiang X, et al. Recent applications of click chemistry in drug discovery. Expert Opin Drug Discov. 2019 Aug;14 (8) :779-789.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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