Human BMP-9/GDF2 protein, S tag
GDF2
Product Specifications
Background
GDF-2 belongs to the TGF- β cytokine family, whose members play an important role during prenatal development and postnatal growth, and the remodeling and maintenance of a variety of tissues and organs. GDF-2 is expressed mainly in non-parenchymal cells of the liver, but is also found in other various cells and tissues. GDF-2 can signal through the ALK1 receptor, and has been implicated in a number of physiologic events including the regulation of the hepatic reticuloendothelial system, glucose homeostasis, iron homeostasis, and the inhibition of angiogenesis. Recombinant Human GDF-2 is a disulfide-linked homodimeric protein consisting of two 110 amino acid polypeptide chains.
Product Name Alternative
GDF-2; BMP-9; GDF2; BMP9
Gene ID
2658
Tag
GDF2
Type
Cytokines and proteins
Applications
S tag
Purity
> 96 % as determined by SDS-PAGE
Activity
Testing in progress
Molecular Formula
12.2 kDa
Molecular Weight
12.2 kDa
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Features & Benefits
Endotoxin : < 1 EU per μg of the protein as determined by the LAL method.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Lyophilized protein product should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage
Protein Length
The recombinant Human GDF2 consists of 110 amino acids and predicts a molecular mass of 12.2 kDa.
Formulation
Lyophilized from sterile 20 mM Tris, 150 mM NaCl, pH 8.0.
Applications Notes
Human
Other Product Names
GDF2, GDF-2, GDF 2, BMP9, BMP-9, BMP 9
Recommended Usage
Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
Preparation
E.coli
Accession Number URL
https://www.uniprot.org/uniprotkb/Q9UK05/entry
AA Sequence
Amino acid sequence derived from Human GDF2 (Ser320-Arg429) (Q9UK05) was expressed with S tag at the N-terminus.
Available Sizes
Curated Selection
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