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Human BMP-9/GDF2 protein, S tag

GDF2

Product Specifications

Background

GDF-2 belongs to the TGF- β cytokine family, whose members play an important role during prenatal development and postnatal growth, and the remodeling and maintenance of a variety of tissues and organs. GDF-2 is expressed mainly in non-parenchymal cells of the liver, but is also found in other various cells and tissues. GDF-2 can signal through the ALK1 receptor, and has been implicated in a number of physiologic events including the regulation of the hepatic reticuloendothelial system, glucose homeostasis, iron homeostasis, and the inhibition of angiogenesis. Recombinant Human GDF-2 is a disulfide-linked homodimeric protein consisting of two 110 amino acid polypeptide chains.

Product Name Alternative

GDF-2; BMP-9; GDF2; BMP9

Gene ID

2658

Tag

GDF2

Type

Cytokines and proteins

Applications

S tag

Purity

> 96 % as determined by SDS-PAGE

Activity

Testing in progress

Molecular Formula

12.2 kDa

Molecular Weight

12.2 kDa

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Features & Benefits

Endotoxin : < 1 EU per μg of the protein as determined by the LAL method.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Lyophilized protein product should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage

Protein Length

The recombinant Human GDF2 consists of 110 amino acids and predicts a molecular mass of 12.2 kDa.

Formulation

Lyophilized from sterile 20 mM Tris, 150 mM NaCl, pH 8.0.

Applications Notes

Human

Other Product Names

GDF2, GDF-2, GDF 2, BMP9, BMP-9, BMP 9

Recommended Usage

Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.

Preparation

E.coli

Accession Number URL

https://www.uniprot.org/uniprotkb/Q9UK05/entry

AA Sequence

Amino acid sequence derived from Human GDF2 (Ser320-Arg429) (Q9UK05) was expressed with S tag at the N-terminus.

Available Sizes

Curated Selection

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