Recombinant Mouse FLT3LG Protein (His Tag)
Product Specifications
Background
FLT3L, also known as flt3 ligand, is a small molecule that acts as a growth factor that increases the number of immune cells by activating the hematopoietic progenitors. In vivo, FLT3L also induces the mobilization of the hematopoietic progenitors and stem cells. This may help the system to kill cancer cells. Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3L controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 -positive classical DCs and their CD103 -positive tissue counterparts.
Abbreviation
FLT3LG
Synonyms
TNFSF; APT1LG; Apo I Ligand; APT1LG1; APTL; CD178; CD95L; Fas-Lg; FL; Flt3 ligand; Flt3-L; FLT3-LG; Fms-Related Tyrosine Kinase 3 ligand; Fms-related tyrosine kinase 3 ligand (Flt3L) ; gld; SL cytokine; soluble Fas Ligand (sFasL) ; Tnfs; TNFSF6; Tnlg1a; Flt3lg; Flt3L; Flt3 ligand
UniProt
P49772
Accession Number
P49772
Expression System
Mammalian
Tag
C-His
Sequence
Gly27-Gln189
Field of Research
Immunology; Stem cells; Signal Transduction; Developmental Biology
Endotoxin
< 1.0 EU/mg of the protein as determined by the LAL method
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/twqqus
Product MSDS
https://789.bio/eb/aWeHlH
Calculated Molecular Weight
17.8 kDa
Observed Molecular Weight
28-35 kDa
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
Species
Mouse
Available Sizes
Curated Selection
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