Recombinant Mouse FLT3LG Protein (His Tag)

Product Specifications

Background

FLT3L, also known as flt3 ligand, is a small molecule that acts as a growth factor that increases the number of immune cells by activating the hematopoietic progenitors. In vivo, FLT3L also induces the mobilization of the hematopoietic progenitors and stem cells. This may help the system to kill cancer cells. Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3L controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 -positive classical DCs and their CD103 -positive tissue counterparts.

Abbreviation

FLT3LG

Synonyms

TNFSF; APT1LG; Apo I Ligand; APT1LG1; APTL; CD178; CD95L; Fas-Lg; FL; Flt3 ligand; Flt3-L; FLT3-LG; Fms-Related Tyrosine Kinase 3 ligand; Fms-related tyrosine kinase 3 ligand (Flt3L) ; gld; SL cytokine; soluble Fas Ligand (sFasL) ; Tnfs; TNFSF6; Tnlg1a; Flt3lg; Flt3L; Flt3 ligand

UniProt

P49772

Accession Number

P49772

Expression System

Mammalian

Tag

C-His

Sequence

Gly27-Gln189

Field of Research

Immunology; Stem cells; Signal Transduction; Developmental Biology

Endotoxin

< 1.0 EU/mg of the protein as determined by the LAL method

Purity

> 95% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.