Lonazolac

Lonazolac is a non-steroidal antirheumatic agent. Anti-inflammatory effects [1].

Product Specifications

CAS Number

[53808-88-1]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Drug Intermediate

Type

Reference compound

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/lonazolac.html

Purity

99.59

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(O)CC1=CN(C2=CC=CC=C2)N=C1C3=CC=C(Cl)C=C3

Molecular Formula

C17H13ClN2O2

Molecular Weight

312.75

Precautions

H302, H315, H319, H335

References & Citations

[1]Trnavský K, et al. [Lonazolac - a new non-steroidal antirheumatic agent. Report of a double-blind crossover clinical study]. Fysiatr Revmatol Vestn. 1983;61 (3) :147-152.|[2]Harras MF, et al. Discovery of new non-acidic lonazolac analogues with COX-2 selectivity as potent anti-inflammatory agents. Medchemcomm. 2019;10 (10) :1775-1788. Published 2019 Jul 22.