STXB2 rabbit pAb

This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2013],

Product Specifications

Background

UniProt

Q15833

Swiss Prot

Q15833

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from human STXB2 AA range: 392-442

Target

STXB2

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA; IHC

Concentration

1 mg/ml

Dilution

WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Buffer

-20°C/1 year

Storage Conditions

-20°C/1 year

Fragment

IgG

Subcellular Location

Cytosol, plasma membrane, integral component of membrane, apical plasma membrane, SNARE complex, specific granule, azurophil granule, zymogen granule membrane, cytolytic granule, extracellular exosome, tertiary granule