Kihadanin A

Kihadanin A (compound 3) is a limonoid NOS3 inhibitor that can be isolated from the methanol extract of Dictamnus dasycarpus root bark. Kihadanin A is useful in the study of hyperuricemia (HUA) [1][2][3].

Product Specifications

CAS Number

[125276-62-2]

UNSPSC

12352005

Target

NO Synthase

Type

Natural Products

Related Pathways

Immunology/Inflammation

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/kihadanin-a.html

Purity

97.0

Solubility

DMSO : ≥ 50 mg/mL

Smiles

C[C@]12[C@]34[C@](C(O[C@](C5=CC(OC5O)=O)([H])[C@@]4(CC[C@]1([H])[C@@]6([C@@](C(C)(OC(C=C6)=O)C)([H])CC2=O)C)C)=O)([H])O3

Molecular Formula

C26H30O9

Molecular Weight

486.51

References & Citations

[1]Guo XX, et al. [Chemical constituents from root barks of Dictamnus dasycarpus and their cytotoxic activities]. Zhongguo Zhong Yao Za Zhi. 2018 Dec;43 (24) :4869-4877. Chinese.|[2]Wang L L, Jiang C S, Fu Y, et al. Two new limonoids from the root bark of Chinese medicinal plant Dictamnus dasycarpus[J]. Helvetica Chimica Acta, 2014, 97 (9) : 1301-1306.|[3]Chen Q, et al. Computational biomedical modeling and screening for prediction of molecular mechanisms of Simiao Pill against hyperuricemia[J]. Journal of Molecular Liquids, 2023, 381: 121827.