S6821
Product Specifications
UNSPSC Description
S6821 is a TAS2R8 antagonist with IC50 value of 0.035 μM. S6821 is not found to be mutagenic or disruptive in vitro, nor is it found to induce micronucleus in bone marrow polychromatic erythrocytes in vivo[1].
Target Antigen
Taste Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/s6821.html
Solubility
10 mM in DMSO
Smiles
O=C1N(C2=CN(CC3=C(C)ON=C3C)N=C2)C(CN1CC4=CC(O)=CC=C4)=O
Molecular Weight
381.39
References & Citations
[1]Karanewsky DS, et al. Toxicological evaluation of two novel bitter modifying flavour compounds: 3-(1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-yl)-1-(3-hydroxybenzyl)imidazolidine-2,4-dione and 3-(1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-yl)-1-(3-hydroxybenzyl)-5,5-dimethylimidazolidine-2,4-dione. Toxicol Rep. 2016 Feb 28;3:310-327.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-139899/S6821-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-139899/
Clinical Information
No Development Reported
CAS Number
1119831-25-2
Available Sizes
Curated Selection
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