Bradykinin (1-5)
Bradykinin (1-5) is a major stable metabolite of Bradykinin , formed by the proteolytic action of angiotensin-converting enzyme (ACE). Bradykinin (1-5) inhibits α- and γ-thrombin-induced platelet aggregation[1].
Product Specifications
CAS Number
23815-89-6
UNSPSC
12352209
Hazard Statement
H302, H315, H319, H335
Target
Drug Metabolite
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Bradykinin_1-5.html
Purity
99.38
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N1[C@@H](CCC1)C(N2[C@@H](CCC2)C(NCC(N[C@@H](CC3=CC=CC=C3)C(O)=O)=O)=O)=O)[C@H](CCCNC(N)=N)N
Molecular Formula
C27H40N8O6
Molecular Weight
572.66
Precautions
H302, H315, H319, H335
References & Citations
[1]Murphey LJ, et al. Bradykinin and its metabolite Bradykinin 1-5 inhibit thrombin-induced platelet aggregation in humans. J Pharmacol Exp Ther. 2006 Sep;318 (3) :1287-92.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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