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Bradykinin (1-5)

Bradykinin (1-5) is a major stable metabolite of Bradykinin (HY-P0206), formed by the proteolytic action of angiotensin-converting enzyme (ACE) [1]. Bradykinin (1-5) inhibits α- and γ-thrombin-induced platelet aggregation[1].

Product Specifications

CAS Number

[23815-89-6]

UNSPSC

12352209

Hazard Statement

H302, H315, H319, H335

Target

Drug Metabolite

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/Bradykinin_1-5.html

Purity

99.38

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(N1[C@@H](CCC1)C(N2[C@@H](CCC2)C(NCC(N[C@@H](CC3=CC=CC=C3)C(O)=O)=O)=O)=O)[C@H](CCCNC(N)=N)N

Molecular Formula

C27H40N8O6

Molecular Weight

572.66

Precautions

H302, H315, H319, H335

References & Citations

[1]Murphey LJ, et al. Bradykinin and its metabolite Bradykinin 1-5 inhibit thrombin-induced platelet aggregation in humans. J Pharmacol Exp Ther. 2006 Sep;318 (3) :1287-92.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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