Thonzonium (bromide)
Thonzonium bromide is an antibacterial agent that is structurally similar to Farnesol. Thonzonium bromide is also a monocationic surface-active agent, which inhibits RANKL-induced osteoclast formation and bone resorption in vitro and prevents LPS-induced bone loss in vivo. Thonzonium bromide inhibits proton transport in a dose-dependent manner (EC50=69 μM)[2][3].
Product Specifications
CAS Number
553-08-2
UNSPSC
12352005
Hazard Statement
H302+H312+H332, H315, H318, H335
Target
Bacterial; Proton Pump
Type
Reference compound
Related Pathways
Anti-infection; Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Thonzonium-bromide.html
Purity
99.86
Solubility
DMSO : ≥ 30 mg/mL|H2O : 100 mg/mL (ultrasonic)
Smiles
CCCCCCCCCCCCCCCC[N+](C)(CCN(CC1=CC=C(OC)C=C1)C2=NC=CC=N2)C.[Br-]
Molecular Formula
C32H55BrN4O
Molecular Weight
591.71
Precautions
H302+H312+H332, H315, H318, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
N-(4,4-Diethoxybutyl)-N-ethylnitrous Amide
CD11b / MAC-1 (Microglial Marker) (ITGAM/3340), Biotin conjugate, 0.1mg/mL
![Pellino 1 (PELI1) Mouse Monoclonal Antibody [Clone ID: OTI3A9]](https://cdn.genprice.uk/products/937/68dd18b9061270361e908115/imageurl/cf807607.webp)
Pellino 1 (PELI1) Mouse Monoclonal Antibody [Clone ID: OTI3A9]
![Gemin 2 (GEMIN2) Mouse Monoclonal Antibody [Clone ID: OTI4C11]](https://cdn.genprice.uk/products/937/68dd18ba061270361e9083e9/imageurl/cf808769.webp)