KRas G12C inhibitor 1

2158297-28-8

12352005

Ras

Reference compound

GPCR/G Protein; MAPK/ERK Pathway

Cancer-Kinase/protease

Cancer

https://www.medchemexpress.com/KRas_G12C_inhibitor_1.html

10 mM in DMSO

C=CC(N1C[C@H](C)N(C2=C3C(CN(C4=C5C=CC=CC5=CC(O)=C4)CC3)=NC(OC[C@H]6N(C)CCC6)=N2)CC1)=O

C31H38N6O3

542.67

[1]Blake J, et al. Kras g12c inhibitors. US 20180072723 A1.

Room temperature

Reference compound1

No Development Reported

K-Ras