AE027
AE027 is a potent inhibitor against both WT and resistant mutation F348Y AChE with the IC50 values of 10 and 43 μM, respectively[1].
Product Specifications
CAS Number
[1011351-65-7]
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ae027.html
Smiles
ClC1=CC(OCO2)=C2C=C1CN(CC3=CC=CO3)CCCN(C)C
Molecular Formula
C18H23ClN2O3
Molecular Weight
350.84
References & Citations
[1]Qin J, et al. Identification of a Novel Inhibitor of Cimex lectularius Acetylcholinesterase. J Agric Food Chem. 2024;72 (22) :12498-12507.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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