7-Ketodeoxycholic Acid

<strong>7-Ketodeoxycholic Acid</strong>_x000D_ <strong>Catalog number:</strong> B2017912_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 25 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 406.56_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> N/A_x000D_ <strong>Keywords:</strong> 3α,12α-Dihydroxy-7-oxo-5β-cholanoic acid, 7-Oxo-3α,12α-dihydroxy-5β-cholanoic acid_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Smirnova E, Muthiah MD, Narayan N, Siddiqui MS, Puri P, Luketic VA, Contos MJ, Idowu M, Chuang JC, Billin AN, Huss RS, Myers RP, Boyett S, Seneshaw M, Min HK, Mirshahi F, Sanyal AJ. Metabolic reprogramming of the intestinal microbiome with functional bile acid changes underlie the development of NAFLD Hepatology. 2022 Dec;76(6):1811-1824._x000D_ 2: Sutherland JD, Williams CN. Bile acid induction of 7 alpha- and 7 beta-hydroxysteroid dehydrogenases in Clostridium limosum J Lipid Res. 1985 Mar;26(3):344-50._x000D_ 3: Liang Z, Hao Y, Yang L, Yuan P, Kang W, Liang T, Gu B, Dong B. The potential of Klebsiella and Escherichia-Shigella and amino acids metabolism to monitor patients with postmenopausal osteoporosis in northwest China BMC Microbiol. 2023 Jul 26;23(1):199._x000D_ 4: Chen H, Li S, Pan B, Liu K, Yu H, Ma C, Qi H, Zhang Y, Huang X, Ouyang D, Xie Z. Qing-Kai-Ling oral liquid alleviated pneumonia via regulation of intestinal flora and metabolites in rats Front Microbiol. 2023 Jun 9;14:1194401._x000D_ 5: Fukiya S, Arata M, Kawashima H, Yoshida D, Kaneko M, Minamida K, Watanabe J, Ogura Y, Uchida K, Itoh K, Wada M, Ito S, Yokota A. Conversion of cholic acid and chenodeoxycholic acid into their 7-oxo derivatives by Bacteroides intestinalis AM-1 isolated from human feces FEMS Microbiol Lett. 2009 Apr;293(2):263-70._x000D_ 6: Poša M. Self-Association of the Anion of 7-Oxodeoxycholic Acid (Bile Salt): How Secondary Micelles Are Formed Int J Mol Sci. 2023 Jul 24;24(14):11853._x000D_ 7: Amuro Y, Yamade W, Yamamoto T, Kudo K, Fujikura M, Maebo A, Hada T, Higashino K. Isocholic acid formation from 7 alpha,12 alpha-dihydroxy-3-keto-5 beta-cholanoic acid with human liver enzyme Biochim Biophys Acta. 1986 Dec 5;879(3):362-8._x000D_ 8: Yu J, Hu Q, Liu J, Luo J, Liu L, Peng X. Metabolites of gut microbiota fermenting Poria cocos polysaccharide alleviates chronic nonbacterial prostatitis in rats Int J Biol Macromol. 2022 Jun 1;209(Pt B):1593-1604._x000D_ 9: Khattab RH, Abo-Hammam RH, Salah M, Hanora AM, Shabayek S, Zakeer S. Multi-omics analysis of fecal samples in colorectal cancer Egyptians patients: a pilot study BMC Microbiol. 2023 Aug 29;23(1):238._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/37468912">10: Du L, Zhang Z, Zhai L, Xu S, Yang W, Huang C, Lin C, Zhong LLD, Bian Z, Zhao L. Altered gut microbiota-host bile acid metabolism in IBS-D patients with liver depression and spleen deficiency pattern Chin Med. 2023 Jul 19;18(1):87. </a>_x000D_ _x000D_ <strong>Products Related to 7-Ketodeoxycholic Acid can be found at</strong> <a href="https://moleculardepot.com/product-category/Chemicals /"> Chemicals </a>