(+) -Plakevulin A
(+) -Plakevulin A (Plakevulin A) is an oxylipin and can be isolated from an Okinawan sponge Plakortis sp. (+) -Plakevulin A inhibits the enzymatic activity of DNA polymerases α and δ. (+) -Plakevulin A induces apoptosis and shows anticancer activity[1].
Product Specifications
CAS Number
518035-27-3
UNSPSC
12352211
Target
Apoptosis; DNA/RNA Synthesis
Type
Natural Products
Related Pathways
Apoptosis; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/plus-plakevulin-a.html
Smiles
COC([C@H]1[C@@](O)(C=C[C@@H]1O)CCCCCCCCCCCCCCCC)=O
Molecular Formula
C23H42O4
Molecular Weight
382.58
References & Citations
[1]Kabasawa M, et al . Plakevulin A induces apoptosis and suppresses IL-6-induced STAT3 activation in HL60 cells. Bioorg Med Chem Lett. 2024 Sep 15;110:129886.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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