Isonipecotic acid
Isonipecotic acid is a GABAA receptor partial agonist[1].
Product Specifications
CAS Number
498-94-2
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/isonipecotic-acid.html
Concentration
10mM
Purity
99.93
Solubility
DMSO : < 1 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
O=C(C1CCNCC1)O
Molecular Formula
C6H11NO2
Molecular Weight
129.16
Precautions
H302, H315, H319, H335
References & Citations
[1]Krehan D, et al. Phosphinic, phosphonic and seleninic acid bioisosteres of isonipecotic acid as novel and selective GABA (C) receptor antagonists. Neurochem Int. 2003 Jun;42 (7) :561-5. |[2]Falch E, et al. GABA-mimetic activity and effects on diazepam binding of aminosulphonic acids structurally related to piperidine-4-sulphonic acid. J Neurochem. 1985 Jan;44 (1) :68-75.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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