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GSK376501A

GSK376501A is a selective peroxisome proliferator-activated receptor gamma (PPARγ) modulator for the treatment of type 2 diabetes mellitus[1].

Product Specifications

CAS Number

[1010412-80-2]

UNSPSC

12352005

Target

PPAR

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/GSK376501A.html

Purity

99.06

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C(N1CC2=CC(OCCOC)=CC(OCCOC)=C2)=C(C3=CC=C(C(C)(C)C)C=C3)C4=C1C=CC=C4)O

Molecular Formula

C32H37NO6

Molecular Weight

531.64

References & Citations

[1]Kae M. Bullock, et al. Process Development and Scale-Up of a PPARγ Agonist: Selection of the Manufacture Route. Org. Process Res. Dev. 2009, 13, 2, 303-309.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PPARγ

Available Sizes

Curated Selection

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