Seneciphylline (Standard)
Seneciphylline (Standard) is the analytical standard of Seneciphylline. This product is intended for research and analytical applications. Seneciphylline is a toxic pyrrolizidine alkaloid in Gynura japonica[1]. Seneciphylline significantly increases the activities of epoxide hydrase and glutathione-S-transferase but causes reduction of cytochrome P-450 and related monooxygenase activities[2].
Product Specifications
CAS Number
480-81-9
UNSPSC
12352005
Target
Cytochrome P450; Glutathione S-transferase; Reference Standards
Type
Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/seneciphylline-standard.html
Smiles
O=C(O[C@]1([H])CCN2[C@]1([H])C(COC([C@](C)(O)C(C/3)=C)=O)=CC2)C3=C/C
Molecular Formula
C18H23NO5
Molecular Weight
333.38
References & Citations
[1]Bandyopadhyay S, et al. Cytotoxicity of Senecio in macrophages is mediated via its induction of oxidative stress. Res Vet Sci. 2009 Aug;87 (1) :85-90.|[2]Kakrani HK, et al. Effect of seneciphylline and senecionine on hepatic drug metabolizing enzymes in rats. J Ethnopharmacol. 1984 Dec;12 (3) :271-8.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
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