L-Cystine-34S2
L-Cystine-34S2 is the 34S-labeled L-Cystine. L-Cystine is an amino acid and intracellular thiol, which plays a critical role in the regulation of cellular processes.
Product Specifications
CAS Number
[113512-08-6]
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite; Ferroptosis
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/l-cystine-34s2.html
Purity
98.0
Solubility
0.1 M HCl : 2.5mg/mL (ultrasonic; adjust pH to 2 with HCl) |0.1 M NaOH : 3.33mg/mL (ultrasonic; warming; adjust pH to 11 with NaOH; heat to 70°C) |10 mM in DMSO|DMSO : ≥ 1mg/mL|H2O : ≥ 0.1mg/mL
Smiles
N[C@@H](C[34S][34S]C[C@@H](C(O)=O)N)C(O)=O
Molecular Formula
C6H12N2O4 34S2
Molecular Weight
244.11
Precautions
H302, H315, H319, H335
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Ohtsu I, et al. Uptake of L-cystine via an ABC transporter contributes defense of oxidative stress in the L-cystine export-dependent manner in Escherichia coli. PLoS One. 2015 Apr 2;10 (3) :e0120619.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
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