L-Cystine-34S2

L-Cystine-34S2 is the 34S-labeled L-Cystine. L-Cystine is an amino acid and intracellular thiol, which plays a critical role in the regulation of cellular processes.

Product Specifications

CAS Number

[113512-08-6]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; Ferroptosis

Type

Isotope-Labeled Compounds

Related Pathways

Apoptosis; Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/l-cystine-34s2.html

Purity

98.0

Solubility

0.1 M HCl : 2.5mg/mL (ultrasonic; adjust pH to 2 with HCl) |0.1 M NaOH : 3.33mg/mL (ultrasonic; warming; adjust pH to 11 with NaOH; heat to 70°C) |10 mM in DMSO|DMSO : ≥ 1mg/mL|H2O : ≥ 0.1mg/mL

Smiles

N[C@@H](C[34S][34S]C[C@@H](C(O)=O)N)C(O)=O

Molecular Formula

C6H12N2O4 34S2

Molecular Weight

244.11

Precautions

H302, H315, H319, H335

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Ohtsu I, et al. Uptake of L-cystine via an ABC transporter contributes defense of oxidative stress in the L-cystine export-dependent manner in Escherichia coli. PLoS One. 2015 Apr 2;10 (3) :e0120619.