Sulfo-Cy5 azide

Sulfo-Cy5 azide is a fluorescent dye and nontargeted contrast agent. Sulfo-Cy5 azide has been used to label and image RNA[1][2]. Sulfo-Cy5 azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Product Specifications

CAS Number

[1782950-80-4]

UNSPSC

12171500

Hazard Statement

H315, H319, H335

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/sulfo-cy5-azide.html

Purity

98.97

Solubility

DMSO : 5 mg/mL (ultrasonic)

Smiles

[N-]=[N+]=NCCCNC(CCCCCN1C2=CC=C(S(=O)(O)=O)C=C2C(C)(C)/C1=C\C=C\C=C\C3=[N+](CCCS(=O)([O-])=O)C4=C(C3(C)C)C=C(S(=O)(O)=O)C=C4)=O

Molecular Formula

C37H48N6O10S3

Molecular Weight

833.01

Precautions

H315, H319, H335

References & Citations

[1]Wang Y, et al. Chain-terminating and clickable NAD⁺ analogues for labeling the target proteins of ADP-ribosyltransferases. Angew Chem Int Ed Engl. 2014 Jul 28;53 (31) :8159-62.|[2]Bruckman MA, et al. Dual-modal magnetic resonance and fluorescence imaging of atherosclerotic plaques in vivo using VCAM-1 targeted tobacco mosaic virus. Nano Lett. 2014 Mar 12;14 (3) :1551-8.