LNA-A (Bz) amidite
LNA-A (Bz) amidite can be used for synthesis of ASOs (antisense oligonucleotides) [1].
Product Specifications
CAS Number
[206055-79-0]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/lna-a-bz-amidite.html
Purity
95.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
COC1=CC=C(C(OC[C@@]2([C@H]3OP(OCCC#N)N(C(C)C)C(C)C)CO[C@@]3([H])[C@H](N4C=NC5=C(NC(C6=CC=CC=C6)=O)N=CN=C54)O2)(C7=CC=C(OC)C=C7)C8=CC=CC=C8)C=C1
Molecular Formula
C48H52N7O8P
Molecular Weight
885.94
Precautions
H302, H315, H319
References & Citations
[1]Yamamoto T, et al. Highly Potent GalNAc-Conjugated Tiny LNA Anti-miRNA-122 Antisense Oligonucleotides. Pharmaceutics. 2021 May 31;13 (6) :817.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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