S12340

S12340 is a a inhibitor of the oxidative modification of low-density lipoprotein and shows protective effect on cardiac cells exposed to oxidative stress[1][2].

Product Specifications

CAS Number

144754-35-8

UNSPSC

12352005

Target

LDLR

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/s12340.html

Smiles

O=C1OC2(CN1)CCN(CC2)CCCSC3=CC(C(C)(C)C)=C(C(C(C)(C)C)=C3)O

Molecular Formula

C24H38N2O3S

Molecular Weight

434.64

References & Citations

[1]Breugnot C, et al. S 12340: a potent inhibitor of the oxidative modification of low-density lipoprotein in vitro and ex vivo in WHHL rabbits. J Pharmacol Exp Ther. 1994;269 (2) :515-520. |[2]Iliou JP, et al. Protective effect of S12340 on cardiac cells exposed to oxidative stress. Eur J Pharmacol. 1993;248 (3) :263-272.