P-Anisic acid

P-Anisic acid (4-Methoxybenzoic acid) is an orally available tyrosinase inhibitor that has antioxidant, anti-anxiety, anti-inflammatory, anti-tumor, anti-diabetic, and preservative properties. p-Anisic acid can be used as a preservative in the cosmetics field[1][2][3][4].

Product Specifications

CAS Number

[100-09-4]

Product Name Alternative

4-Methoxybenzoic acid; Draconic acid

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Bacterial; Endogenous Metabolite; Tyrosinase

Type

Natural Products

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Cancer; Infection; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/p-anisic-acid.html

Concentration

10mM

Purity

99.79

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(O)C1=CC=C(OC)C=C1

Molecular Formula

C8H8O3

Molecular Weight

152.15

Precautions

H302, H315, H319, H335

References & Citations

[1]DeWeerd K, et al. Metabolism of the 18O-methoxy substituent of 3-methoxybenzoic acid and other unlabeled methoxybenzoic acids by anaerobic bacteria. Appl Environ Microbiol. 1988 May;54 (5) :1237-42.|[2]Gandhi P J, et al. Transmission of p-anisic acid through nanofiltration and goat membranes[J]. Desalination, 2013, 315: 46-60.|[3]K Nakamura, et al. Anxiolytic effects of aniracetam in three different mouse models of anxiety and the underlying mechanism. Eur J Pharmacol. 2001 May 18;420 (1) :33-43.|[4]Vishal Vora, et al. Anti-Diabetic and Insulinotropic Effects of p-Anisic Acid in High-Fat Diet and Streptozotocin Induced Type-2 Diabetic Rats. Chem Biodivers. 2024 Aug 29:e202401575.