Human Maspin (Highly Pure, Recombinant)

<strong>Human Maspin (Highly Pure, Recombinant)</strong>_x000D_ <strong>Catalog number:</strong> B2010274_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Volume/Weight:</strong> 10 ug_x000D_ <strong>pH:</strong> 7.4 upon reconstitution_x000D_ <strong>Supplied as:</strong> Lyophilized powder_x000D_ <strong>Appearance:</strong> Powder_x000D_ <strong>Applications:</strong> highly pure human Maspin (expressed in E. coli). This 42 kDa protein has been shown to inhibit the invasion and motility of mammary tumors._x000D_ <strong>Storage:</strong> -20C_x000D_ <strong>Keywords:</strong> rHuMaspin; Serpin B5; PI-5_x000D_ <strong>Grade:</strong> Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Bernardo MM, Dzinic SH, Matta MJ, Dean I, Saker L, Sheng S. The Opportunity_x000D_ of Precision Medicine for Breast Cancer With Context-Sensitive Tumor Suppressor_x000D_ Maspin. J Cell Biochem. 2017 Jul;118(7):1639-1647._x000D_ _x000D_ 2: Mahajan N, Hoover B, Rajendram M, Shi HY, Kawasaki K, Weibel DB, Zhang M._x000D_ Maspin binds to cardiolipin in mitochondria and triggers apoptosis. FASEB J._x000D_ 2019 May;33(5):6354-6364._x000D_ _x000D_ 3: Zhang Y, Liu H, Shi X, Qiao F, Zeng W, Feng L, Deng D, Liu H, Wu Y. Maspin_x000D_ impairs the function of endothelial cells: an implying pathway of preeclampsia._x000D_ BMC Pregnancy Childbirth. 2017 Sep 29;17(1):328._x000D_ _x000D_ 4: Dzinic SH, Bernardo MM, Oliveira DS, Wahba M, Sakr W, Sheng S. Tumor_x000D_ suppressor maspin as a modulator of host immune response to cancer. Bosn J Basic_x000D_ Med Sci. 2015 Oct 25;15(4):1-6._x000D_ _x000D_ 5: Wang N, Chang LL. Maspin suppresses cell invasion and migration in gastric_x000D_ cancer through inhibiting EMT and angiogenesis via ITGB1/FAK pathway. Hum Cell._x000D_ 2020 Jul;33(3):663-675._x000D_ _x000D_ 6: Shi X, Liu Q, Liu H, Deng D, Qiao F, Wu Y. Effects of shRNA Targeting Maspin_x000D_ on the Invasion of Extravillous Trophoblast Cell. Am J Perinatol. 2017_x000D_ Aug;34(10):966-973._x000D_ _x000D_ 7: Baghel K, Kazmi HR, Chandra A, Raj S, Srivastava RN. Significance of_x000D_ methylation status of MASPIN gene and its protein expression in prognosis of_x000D_ gallbladder cancer. Asia Pac J Clin Oncol. 2019 Oct;15(5):e120-e125._x000D_ _x000D_ 8: Wang Y, Sun L, Song Z, Wang D, Bao Y, Li Y. Maspin inhibits macrophage_x000D_ phagocytosis and enhances inflammatory cytokine production via activation of NF-_x000D_ κB signaling. Mol Immunol. 2017 Feb;82:94-103._x000D_ _x000D_ 9: Helal DS, El-Guindy DM. Maspin expression and subcellular localization in_x000D_ invasive ductal carcinoma of the breast: Prognostic significance and relation to_x000D_ microvessel density. J Egypt Natl Canc Inst. 2017 Dec;29(4):177-183._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/26067133/">10: Gurzu S, Kadar Z, Sugimura H, Orlowska J, Bara T, Bara T Jr, Szederjesi J,_x000D_ Jung I. Maspin-related Orchestration of Aggressiveness of Gastric Cancer. Appl_x000D_ Immunohistochem Mol Morphol. 2016 May-Jun;24(5):326-36. </a>_x000D_ _x000D_ <strong>Products Related to Maspin (Human, Recombinant) </strong> <a href="https://moleculardepot.com/product-category/Proteins/">: Proteins</a>