JCP-170

JCP-170, a substituted chloroisocoumarin, is an ABHD6 inhibitor. JCP-170 robustly and reproducibly inhibits metastatic seeding of the murine cell line 0688M and both human pancreatic ductal adenocarcinoma (PDAC) cell lines[1].

Product Specifications

CAS Number

[120218-98-6]

UNSPSC

12352005

Target

MAGL

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/jcp-170.html

Smiles

O=C(C(C1=CC=CC=C1)C2=CC=CC=C2)NC3=CC=C(C(Cl)=C(OC4=O)OC)C4=C3

Molecular Formula

C24H18ClNO4

Molecular Weight

419.86

References & Citations

[1]Grüner BM, et al. An in vivo multiplexed small-molecule screening platform. Nat Methods. 2016 Oct;13 (10) :883-889.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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