SHP2-IN-28
Product Specifications
UNSPSC Description
SHP2-IN-28 (Compound 7188-0011) is an inhibitor of SHP2 (IC50=54.31 μM). SHP2-IN-28 exerts its inhibitory effect by binding to the variable site of SHP2 with high selectivity[1].
Target Antigen
SHP2
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/shp2-in-28.html
Solubility
10 mM in DMSO
Smiles
O=C(/C(C1=CC=CC=C1)=N/O)NCC2CCNCC2
Molecular Weight
261.32
References & Citations
[1]Yuan Z et al. Discovery of a novel SHP2 allosteric inhibitor using virtual screening, FMO calculation, and molecular dynamic simulation. J Mol Model. 2024 Apr 13;30(5):131.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-162476/SHP2-IN-28-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-162476/
Clinical Information
No Development Reported
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