Ceforanide

Ceforanide is a semisynthetic parental cephalosporin antibiotic, derived from 7-aminocephalosporanic acid. Ceforanide has antibacterial activity and is a potent inhibitor of most species of streptococci, excluding enterococci[1][2].

Product Specifications

CAS Number

[60925-61-3]

UNSPSC

12352005

Hazard Statement

H317, H334

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/ceforanide.html

Purity

99.23

Solubility

DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(C(N12)=C(CSC3=NN=NN3CC(O)=O)CS[C@]2([H])[C@H](NC(CC4=CC=CC=C4CN)=O)C1=O)O

Molecular Formula

C20H21N7O6S2

Molecular Weight

519.55

Precautions

H317, H334

References & Citations

[1]Campoli-Richards DM, et al. Ceforanide. A review of its antibacterial activity, pharmacokinetic properties and clinical efficacy. Drugs. 1987 Oct;34 (4) :411-37.|[2]Burch, K. H., et al., (1979) . Ceforanide: in vitro and clinical evaluation. Antimicrobial agents and chemotherapy, 16 (3), 386–391.