Anticancer agent 214
Anticancer agent 214 (2) is a Camptothecin compound, with IC50 values of 2.6 nM and 15.7 nM in MCF-7 cells and MDA-MB-231 cells, respectively[1].
Product Specifications
CAS Number
[2916404-95-8]
UNSPSC
12352005
Target
Topoisomerase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-214.html
Smiles
C[C@@H](C1=C2C(C(N3C2)=CC([C@](O)(C(OC4)=O)CC)=C4C3=O)=NC5=CC(F)=C(C)C=C51)N
Molecular Formula
C23H22FN3O4
Molecular Weight
423.44
References & Citations
[1]Furao Zhang, et al. Camptothecin compound, preparation method therefor and use thereof. Patent. WO2023030364.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-158387/Anticancer-agent-214-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-158387/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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