TC AQP1 1
TC AQP1 1 (m-Phenylenediacrylic acid) is a potent AQP1 inhibitor. TC AQP1 1 inhibits AQP1-mediated water flux in oocytes, with an IC50 of 8 μM[1].
Product Specifications
CAS Number
[37710-81-9]
Product Name Alternative
M-Phenylenediacrylic acid; m-Benzenediacrylic acid
UNSPSC
12352005
Hazard Statement
H302, H312, H332
Target
Aquaporin
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/tc-aqp1-1.html
Concentration
10mM
Purity
98.03
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
OC(/C=C/C1=CC(/C=C/C(O)=O)=CC=C1)=O
Molecular Formula
C12H10O4
Molecular Weight
218.21
Precautions
H302, H312, H332
References & Citations
[1]Salman MM, et al. Recent breakthroughs and future directions in drugging aquaporins. Trends Pharmacol Sci. 2022 Jan;43 (1) :30-42.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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