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TC AQP1 1

TC AQP1 1 (m-Phenylenediacrylic acid) is a potent AQP1 inhibitor. TC AQP1 1 inhibits AQP1-mediated water flux in oocytes, with an IC50 of 8 μM[1].

Product Specifications

CAS Number

37710-81-9

Product Name Alternative

M-Phenylenediacrylic acid; m-Benzenediacrylic acid

UNSPSC

12352005

Hazard Statement

H302, H312, H332

Target

Aquaporin

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/tc-aqp1-1.html

Concentration

10mM

Purity

98.03

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

OC(/C=C/C1=CC(/C=C/C(O)=O)=CC=C1)=O

Molecular Formula

C12H10O4

Molecular Weight

218.21

Precautions

H302, H312, H332

References & Citations

[1]Salman MM, et al. Recent breakthroughs and future directions in drugging aquaporins. Trends Pharmacol Sci. 2022 Jan;43 (1) :30-42.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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