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Hepcidin-25 (human)

Hepcidin-25 (human) is an iron metabolism modulator. Hepcidin-25 (human) shows anti-inflammatory and anti-bacterial activity via modulation of iron-mediated oxidant injury[1].

Product Specifications

CAS Number

[1356390-47-0]

UNSPSC

12352209

Hazard Statement

H315-H319-H335

Target

Endogenous Metabolite; Hepcidin

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/hepcidin-25-human.html

Solubility

10 mM in DMSO

Smiles

C([C@@H](NC([C@H](CC1=CN=CN1)NC([C@@H](NC([C@H](CC(O)=O)N)=O)[C@@H](C)O)=O)=O)CC2=CC=CC=C2)(=O)N3[C@H](C(N[C@H](C(N[C@@H]4C(=O)N[C@@]([C@H](CC)C)(C(=O)N[C@@H](CC5=CC=CC=C5)C(=O)N[C@@]6(C(=O)N[C@]7(CSSC[C@]8(C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@](C(=O)N[C@H](C(N[C@H](C(N[C@@H]([C@@H](C)O)C(O)=O)=O)CCCCN)=O)CSSC4)(CSSC[C@@](C(=O)N[C@@H](CC9=CN=CN9)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N8)(NC(=O)[C@](CSSC6)(NC(=O)CNC7=O)[H])[H])[H])[H])[H])[H])[H])=O)[C@H](CC)C)=O)CCC3

Molecular Formula

C113H170N34O31S9

Molecular Weight

2789.35

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

References & Citations

[1]Ueda N, et al. Role of Hepcidin-25 in Chronic Kidney Disease: Anemia and Beyond. Curr Med Chem. 2017;24 (14) :1417-1452.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Curated Selection

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