LPH-5
LPH-5 is a selective 5-HT2A receptor agonist (EC50=190 nM) . LPH-5 works by selectively activating the 5-HT2A receptor, which may be involved in regulating mood, perception, and other central nervous system functions associated with the 5-HT2A receptor. LPH-5 can be used to further explore the 5-HT2A receptor in psychiatric disorders, including depression, anxiety, and substance abuse disorders[1].
Product Specifications
CAS Number
2641630-97-7
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/lph-5.html
Smiles
COC1=C(C=C(C(C(F)(F)F)=C1)OC)[C@]2(CNCCC2)[H]
Molecular Formula
C14H18F3NO2
Molecular Weight
289.29
References & Citations
[1]M. Ro̷rsted E, et al. Discovery and Structure–Activity Relationships of 2, 5-Dimethoxyphenylpiperidines as Selective Serotonin 5-HT2A Receptor Agonists[J]. Journal of Medicinal Chemistry, 2024.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
5-HT2 Receptor
Available Sizes
Frequently Asked Questions
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