Leonurine (hydrochloride)
Leonurine hydrochloride is an alkaloid isolated from Leonurus artemisia, with anti-oxidative and anti-inflammatory.
Product Specifications
CAS Number
24735-18-0
Product Name Alternative
SCM-198 hydrochloride
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Autophagy; Toll-like Receptor (TLR)
Type
Natural Products
Related Pathways
Autophagy; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/Leonurine-hydrochloride.html
Purity
99.43
Solubility
DMSO : ≥ 100 mg/mL|H2O : 5 mg/mL (ultrasonic)
Smiles
O=C(OCCCCNC(N)=N)C1=CC(OC)=C(O)C(OC)=C1.[H]Cl
Molecular Formula
C14H22ClN3O5
Molecular Weight
347.79
Precautions
H302, H315, H319, H335
References & Citations
[1]Jiang T, et al. Leonurine Prevents Atherosclerosis Via Promoting the Expression of ABCA1 and ABCG1 in a Pparγ/Lxrα Signaling Pathway-Dependent Manner. Cell Physiol Biochem. 2017;43 (4) :1703-1717.|[2]Zhang L, et al. Novel hepatoprotective role of Leonurine hydrochloride against experimental non-alcoholic steatohepatitis mediated via AMPK/SREBP1 signaling pathway. Biomed Pharmacother. 2018 Dec 7;110:571-581.|[3]Hu ZC, et al. Inhibition of PI3K/Akt/NF-κB signaling with leonurine for ameliorating the progression of osteoarthritis: In vitro and in vivo studies. J Cell Physiol. 2018 Nov 11.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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