7-Hydroxy-3,4-dihydro-2 (1H) -quinolinone
7-Hydroxy- 3, 4- dihydro- 2 (1H) - quinolinone (3,4-Dihydro-7-hydroxy-2 (1H) -quinolinone) is a weak MAO-A inhibitor, with an IC50 of 183 μM, and has no effect on MAO-B[1].
Product Specifications
CAS Number
22246-18-0
Product Name Alternative
3,4-Dihydro-7-hydroxy-2 (1H) -quinolinone
UNSPSC
12352005
Hazard Statement
H302, H317, H412
Target
Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/7-Hydroxy-3,4-dihydro-2_1H_-quinolinone.html
Purity
99.96
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 1 mg/mL (ultrasonic)
Smiles
O=C1NC2=C(C=CC(O)=C2)CC1
Molecular Formula
C9H9NO2
Molecular Weight
163.18
Precautions
H302, H317, H412
References & Citations
[1]Meiring L, et al. Inhibition of monoamine oxidase by 3,4-dihydro-2 (1H) -quinolinone derivatives. Bioorg Med Chem Lett. 2013 Oct 15;23 (20) :5498-502.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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