7-Hydroxy-3,4-dihydro-2 (1H) -quinolinone

7-Hydroxy- 3, 4- dihydro- 2 (1H) - quinolinone (3,4-Dihydro-7-hydroxy-2 (1H) -quinolinone) is a weak MAO-A inhibitor, with an IC50 of 183 μM, and has no effect on MAO-B[1].

Product Specifications

CAS Number

[22246-18-0]

Product Name Alternative

3,4-Dihydro-7-hydroxy-2 (1H) -quinolinone

UNSPSC

12352005

Hazard Statement

H302, H317, H412

Target

Monoamine Oxidase

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/7-Hydroxy-3,4-dihydro-2_1H_-quinolinone.html

Purity

99.96

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 1 mg/mL (ultrasonic)

Smiles

O=C1NC2=C(C=CC(O)=C2)CC1

Molecular Formula

C9H9NO2

Molecular Weight

163.18

Precautions

H302, H317, H412

References & Citations

[1]Meiring L, et al. Inhibition of monoamine oxidase by 3,4-dihydro-2 (1H) -quinolinone derivatives. Bioorg Med Chem Lett. 2013 Oct 15;23 (20) :5498-502.